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Big doses (three or even more moments the equal efficient human dose) of morphine, meperidine, and atropine elevated the depth and extended the period of anesthesia made by an ordinary anesthetizing dose of ketamine hydrochloride in Rhesus monkeys.

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If a longer effect is ideal, further increments is usually administered intravenously or intramuscularly to keep up anesthesia without the need of developing important cumulative effects.

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It ought to be recognized the much larger the entire dose of ketamine hydrochloride administered, the longer would be the time to finish Restoration.

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